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Both ascending and descending fibers of the MLF originating in various nuclei show a topographic distribution in the MLF. In general, results similar to those obtained in the rabbit seem to exist in the MLF of man. Accordingly, in the case of lesion in the MLF, this pattern should always be considered in order to determine the site of the lesion.

THE LOCALIZATION PATTERN OF NERVE FIBERS PROJECTING INTO THE MEDIAL LONGITUDINAL FASCICULUS