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Purpose: Choroidal neovascular membrane can arise secondary to many other causes other than aging. No cases have been reported on CNVM post vitrectomy for retinal detachment. We present two cases of classical sub-foveal CNVM occurring following VR surgery in retinal detachment patients. Method: A retrospective analysis of databases was done at our centre. Around 800 VR surgeries were done of which 300 were macular surgeries over a period 3 years from 2014 to 2017. All cases were operated by a single surgeon with 3 port 23- gauge vitrectomy. Two cases of retinal detachment developed CNVM after silicon oil removal. Results: The prevalence of CNVM formation after macular surgery at our institution was 2 out of 300 (0.66%) patients from a period of Jan 2015 to Dec 2018. The time period for the formation of CNVM was around 7 months after vitrectomy and 2 weeks after Silicon oil removal in both patients. Discussion: After all the literature search for knowing the reported cases and the pathophysiology for CNVM occurring post Retinal detachment surgery we attribute it to post-operative inflammation, silicon oil induced retinal toxicity, weakening of retinal layers and retinal photo toxicity. Conclusion: Despite the fact that CNV post retinal detachment surgery is rare, we suggest that it must be included in the consent process prior to surgery, as patients should be warned about potential guarded visual outcome. Further research is needed to evaluate the possible mechanisms and risk factors that lead to formation of CNVM after retinal detachment surgery.

Choroidal neovascular membrane following vitreoretinal surgery for retinal detachment