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The Editor  Current Oncology  October 29, 2012  The recent article by Wong et al. was highly interesting1. Exercise—especially aerobic exercise—has several beneficial effects in breast cancer patients and survivors besides mitigating chest wall pain.  Exercise regimens result in a reduction of progesterone and estrogen levels in premenopausal women at high risk of developing breast malignancies, thus attenuating the risk of breast cancers developing. In fact, Kossman et al.2 reported that, after exercise, total progesterone exposure is decreased by nearly 24%. Exercise not only reduces breast tumour size, but also number3. In addition, cardiotoxic side effects secondary to chemotherapy with anthracyclines in breast cancer patients can be significantly decreased and attenuated by the initiation of aerobic exercise regimens in these patients4. Similarly, Chen et al. showed that exercise in the initial 3 years after a diagnosis of breast cancer is inversely related to disease-specific mortality, with a hazard ratio of 0.65.  The maximum aerobic capacity is significantly increased in breast cancer survivors after moderate-intensity aerobic exercise, even for durations as short as 3 weeks6. Similarly, the restore study showed that tailor-made exercise regimens initiated within the initial 3 months after breast surgery significantly enhance physical functioning without affecting quality of life7. Similarly, femoral neck bone mass loss in breast cancer patients in the premenopausal age groups is almost completely mitigated with the use of aerobic exercise regimens inclusive of circuit training and jumping8.  In addition, exercises targeting the upper extremities markedly improved the range of motion of the shoulder joint in breast cancer survivors9. Similarly, the early initiation of exercise in the postoperative period is associated with attenuated risk for the development of lymphedema10.  The above examples clearly highlight the advantages of exercise in breast cancer patients and survivors and the need for further studies to fully elaborate the beneficial effects of exercise.

Advantages of Exercise in Breast Cancer Patients and Survivors in Addition to Its Mitigating Effect on Chest Wall Pain