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166 DOI: 10.37398/JSR.2021.650121 Abstract: To evaluate Insilico interaction efficacy of Terminalia chebula phytocompounds with alpha haemolysin of Multiple Drug Resistance Uropathogenic Escherichia coli (MDRUPEC) strains. In the present investigation, Insilico interaction profile of the phytocompounds retrieved from PubChem amalgam database such as tannic acid, ellagic acid and gallic acid from Haritaki were evaluated against toxic protein Haemolysin (HlyA) of MDRUPEC strains. The glide module of Schrodinger was used to study the docking interaction of the compounds. Based on the Insilico research findings, ellagic acid found to be the best docking phytocompound with the scoring efficiency of -5.44. This innovative approach formed a framework for the development of new pharmacologically active phytocompounds as therapeutic agents for the effective aid for the illness of human population by the MDR strains.

Insilico Interaction Profile of Terminalia chebula Phytocompounds with Alpha Haemolysin of Multiple Drug Resistant Uropathogenic Escherichia coli