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Melanoma is a malignant disease of the cutaneous organ that shows significant aggression, resistance to treatment and increased mortality. Melanin and B-type ultraviolet radiation are key factors in the appearance and development of melanoma. In this study, the melanocyte and two melanoma tumor cells behaviour was evaluated in the presence of UVB radiation. The results highlighted the significant impairment of melanin-producing malignant cells, COLO-829, at both radiation doses tested.

Melanin and Behaviour of Melanoma-related Cell Lines in the Presence of Ultraviolet B Type Radiation