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The authors conducted clinical and immunological research on the identification of сytokine factors of inflammation and regeneration in patients with frontal bone trauma (29) and practically healthy donors (11). Factors of inflammation (interleukin-1β, γ-interferon), anti-inflammation and regeneration (interleukin-34 and transforming growth factor – TGF-1β) were determined in the blood serum by ELISA.It was found that the content of the factor of regeneration decreases and the levels of anti-inflammatory cytokines increase in the blood serum of the patients with frontal traumas with frontal sinus damage.

Clinical and immunological studies of humoral factors of inflammation and regeneration in patients with injuries of the frontal and basal area