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The role of multi-modality pre-operative treatment of advanced, resectable squamous cell carcinoma of the head and neck is not standardized. Low-dose, fractionated cisplatin with simultaneous radiation therapy is one therapeutic approach. To evaluate simultaneous fractionated cisplatin and radiation therapy for advanced operable Stage III and IV squamous cell carcinoma (SCC) of the base of tongue (BOT) and hypopharynx.

Pre-Operative Simultaneous Fractionated Cisplatin and Radiation Therapy in the Treatment of Advanced Stage III and IV Squamous Cell Carcinoma of the Base of Tongue and Hypopharynx