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A total of 22 sure homozygotes were gathered (13 from the Mediterranean countries and 9 from the American ones) 3 proven and 7 highly probable homozygotes have been reported in North America, all in the USA. The ethnic origin of these patients was African-American.

Factor VII Arg304Gln (FVII Padua) in North and South Americas: The Influence of Past "Forced" or Spontaneous Migrations