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Pyoderma gangrenosum (PG) is a rare, sterile, inflammatory neutrophilic dermatosis that is painful with necrotizing ulcerations. It can be idiopathic or in association with systemic disease such as PG, acne, hidradenitis suppurativa (PASH) syndrome. PASH syndrome itself is rare, consists of multiple neutrophilic dermatoses, and is thought to be caused by an underlying genetic predisposition. Due to recurrence and poor healing, treatment for PG ranges from wound care to topical and oral medications to surgical procedures.

journal of gastroenterology research

Dehydrated Human Amnion/Chorion Membrane Allograft for Treatment of Recalcitrant Pyoderma Gangrenosum in PASH Syndrome and Systemic Lupus Erythematosus