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Purpose: The primary aim of this study was the parameterization of our Geant4 Application for Tomographic Emission (GATE) linear accelerator (linac) model for the Varian Clinac 23 EX 6 MV photon beam via the comparison to the experimental PTW semiflex 31010 Percentage Depth Doses and cross-plane dose profiles for depths of dmax = 1.5, 5 and 10 cm for field sizes ranging from 30 × 30 to 3 × 3 cm2 defined at isocenter. Material methods: The GATE v7.0 geometric tools were used for designing the Varian Clinac 23 EX linac head according to manufacturer’s blueprints. Also, the GATE software tool Dose Actor divided the water phantom in dosels of 5 × 5 × 5 mm3 volume scoring the energy, dose and statistical uncertainty in each of them. The use of Bremsstrahlung Splitting technique with energy and direction filters was implemented for improving simulation efficiency but simultaneously conserving the physics accuracy of simulations. The vast number of simulations were run with the gate lab application of virtual imaging platform. The mean number of simulated electron particles in each simulation run was 7 billions and the mean simulation duration time 12 h. Results: The mean energy of 6.2 MeV, the focal spot size of 1.4 mm and the flattening filter material density of 10.5 g cm-3, were the final parameters values of our gate linac model that guarantee a good agreement to experimental ones, giving a simulation statistical uncertainty below 1%, local dose differences for cross plane dose profiles and PDDs, past the depth of maximum dose, better than 2% and identical beam quality index ( ) 20 10 TPR . Conclusions: The consistent set of the main characteristics of the initial electron beam and the flattening filter material density in combination with all gate parameters tested in a broad range of field sizes provides a well-validation of our gate linac model.

Monte Carlo Simulation of 6MV Varian Clinac Photon Beam Using GEANT4-GATE