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Contrast-Induced Acute Kidney Injury (CI-AKI) is the third most common cause of in-hospital acute kidney injury (AKI) and accounts for 10% of total cases [1]. CI-AKI continues to be one of the most common major adverse side effect of cardiac catheterization, and is associated with shortand long-term morbidity and mortality [2,3]. This is particularly true in the population presenting with acute ST-Elevation Myocardial Infarction (STEMI). A recent study evaluating the epidemiology of CI-AKI in over 8000 patients undergoing PCI found that CI-AKI occurred in 12% of STEMI, which was significantly higher compared with patients undergoing non-emergent catheterization (9.2% in unstable angina and NSTEMI patients and 4.5% undergoing elective PCI). Even in patients with baseline Glomerular Filtration Rate (GFR)>60, the incidence of CI-AKI in the STEMI patients was 9.2% [4]. Such a high incidence of this complication invokes the need to define measures to decrease the occurrence of CI-AKI in patients presenting with STEMI.

sm journal of nephrology and therapeutics

Evaluating the Association between Hyperuricemia and Contrast InducedAcute Kidney Injury in Patients with Acute ST-Elevation Myocardial Infarction Undergoing Percutaneous Coronary Intervention