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Melanocytes are the pigment containing cells in the body that lead to malignant melanoma. Melanomas typically occur in the skin but may also occur in the mouth, intestines, or eye rarely. Survival of patients with malignant melanoma is directly related to early detection. Melanoma that is confined to the epidermis (in-situ) carries no risk of death and a thin melanoma lesion carries very little risk of metastatic spread. Again, the disease can be caused up to 25% from moles. It also results from a number of genetic mutations that are hereditary. For example, some rare genes have a relatively high risk of causing melanoma; some more common genes, such as a gene called MC1R that causes red hair, have a relatively lower elevated risk. Hence the need for gene therapy to treat Melanoma is important [1].

Gene Therapy for Treatment of Melanoma Cancer