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Diabetes mellitus can cause various complications and eventually leads to death.1,2 According to Riskesdas 20133, the prevalence of diabetes mellitus in Indonesia was 2.1%, higher than it was in 2007, which was 1.1%. The International Diabetes Federation (IDF) stated that approximately 5 million people died because of diabetes mellitus in 2015 globally.2 One of the most common complications of diabetes mellitus is diabetic foot ulcers (DFU). DFU can cause amputation, which decreases the patient’s quality of life and increase the mortality rate.4 DFU has been a global health problem due to it can cause a decrease in quality of life in diabetic patients.5,6 Low vitamin D serum levels were found in patients with DFU.7 Vitamin D is known to be correlated with wound healing and insulin resistance and is useful in predicting DFU.8 The effects of vitamin D supplementation are including phagocytosis induction, macrophage activation, insulin receptor expression activation, and cytokines down regulation.9-11 Vitamin D is also known to have an ability to affect the pancreatic beta cells and increase insulin sensitivity.12 The result evalution of vitamin D serum levels is not routinely done in DFU patients in Indonesia. The correlation between serum levels of vitamin D and DFU degree of severity needs to be studied in order to know the importance of its examination.

Correlation between Serum Level of Vitamin D and Severity Degree of Diabetic Foot Ulcer in Patients with Normal Ankle Brachial Index