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OBJECTIVEThe aim: to investigate the copper content in blood serum of children with different short stature types.PATIENTS AND METHODSMaterials and methods: In the first stage, a comprehensive survey of 258 school children aged 7-11 was carried out in Chernivtsi to assess the prevalence of short staturechildren of school-age. In the second stage, a comparative study of 42 children aged 3 to 15 years with different types of short stature was conducted. Research: anthropometry, determination of growth hormone, TSH, IGF-1, and copper level in blood plasma.RESULTSResults: The largest growth rate in children with somatotropic insufficiency, the syndrome of a biologically inactive growth hormone ranged from 4.1 cm/year to 1.6 cm/year, the ones with a family constitutional low-growth - from 5.7 cm/year to 3.3 cm/year. In 57 cases, that makes 1% of children with short stature, the blood plasma level of copper made less and rated 0.89 ± 0.04 μg / ml, which is believed to be lower (pу0,001) the average copper in children of the control group - 1.07 ± 0.02 μg / ml. Indices of copper in blood plasma in children with somatotropic insufficiency were the lowest and averaged 0.75 ± 0.03 μg / l, p<0.05.CONCLUSIONConclusions: The lack of copper in the blood plasma is observed in most children with short stature, which indicates the need for appropriate correction.

The copper content in the blood plasma of children with different types of short stature