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J. Selva Andina Res. Soc. 2020; 11(2):114-129. In This research has been developed in the Biodiversity and Geographyc Information System Laboratory at the Faculty of Biological Sciences of San Cristobal de Huamanga University. Forty experimental units of 1L round plastic containers were built with different concentrations of anti-inflammatory drugs and control units. Ten immature specimens of Rhinella spinulosa (Wiegman 1843) about 2 to 25 cm were placed in each experimental unit to determine mortality rates during continuous exposure at 24 and 48 h. As a result, mortality percentages obtained were statistically different (p <0.05); ibuprofen has generated a mortality of 43.33 and 100% at 40 and 80 mg/L of concentration for 24 hours and 40, 76.67 and 100% a 10; 20 and 40 mg/L of concentration for 48 hours, naproxen 3.33 and 13.33% at 32 and 64 mg/L of concentration for 24 hours and 23.33; 26.67; 50 and 73.33% at 8, 16; 32 y 64 mg/L of concentration for 48 hours, and diclofenac 13.33 y 100% at 60 y 120 mg/L for 24 hours and 23.33; 60, 90 y 100% at 15; 30; 60 y 120 mg/L for 48 hours. The LC50 was respectively: 68.6 mg / L, 106.6 mg / L and 120 mg / L for 24 hours and 13.47 mg / L, 104.6 mg / L and 29.8 mg / L for 48 hours, showing that as the exposure time decreases the lethal concentration increase. 2020. Journal of the Selva Andina Research Society®. Bolivia. All rights reserved. ID del artículo: 133/JSARS/2020 Historial del artículo. Recibido febrero 2020. Devuelto abril 2020. Aceptado junio 2020. Disponible en línea, agosto 2020. Editado por: Selva Andina Research Society

Mortalidad en estadios juveniles del Sapo Espinoso Andino Rhinella spinulosa (Wiegman 1843)