English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Tools annual

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Presents the access of premium content as premium feature

Premium Content

Global: Zendy Plus annual

Global: Zendy Free Plan

ABSTRACTBackground: Cervical cancer rates in North Africa have risen in the last 10 years, suggesting thatthis region might benefit from cervical cancer screening and HPV vaccination programs. To assessthe potential benefits of cervical cancer screening and HPV vaccination in North African countries,country-specific data on the prevalence and burden of HPV-related conditions are needed.Objectives: To describe the patterns and estimate the costs of management of cervical cancer, cervicalintraepithelial neoplasia (CIN), and genital warts in Algeria.Methods: This was a descriptive analysis of questionnaire data obtained from a panel of 15 oncologists,gynecologists, and dermatologists (n=5 each). Data on diagnostic and treatment patterns, recurrence,and healthcare resource use (HCRU) were obtained. The costs (in Algerian dinars) associated withdiagnosis, treatment, and recurrence were estimated.Results: Diagnosis of CIN was obtained by cytology tests or lesion biopsies; for cervical cancer, lesionbiopsies, MRI, and CT scans were the most common diagnostic tests. For CIN, 70% of gynecologistsand oncologists regularly or always used conization as a treatment. Treatments used regularly or alwaysfor cervical cancer included chemotherapy (80%), hysterectomy (70%), and radiation (70%). AnnualHCRU per institution included 20 outpatient visits and 15 hospitalizations for CIN, and 50 outpatientvisits and 11 hospitalizations for cervical cancer. For genital warts, diagnostic tests performed regularly oralways included assays for hepatitis B, hepatitis C, HIV, and syphilis; cervical cytology; and colposcopy.Cryotherapy was the universal first-line treatment. Median per-patient costs associated with diagnosis,treatment, and recurrence were 6750, 19 750, and 77 750, respectively, for CIN; 53 750, 650 000, and431 250, respectively, for cervical cancer; and 16 075, 15 500, and 9250, respectively, for genital warts.Discussion: These results give an estimate of the HCRU and cost of cervical cancer, CIN, and genitalwarts and highlight the need to assess more precisely the epidemiology of these diseases in Algeria.Conclusions: This study investigated the management of patients with cervical cancer, CIN, or genitalwarts in Algeria and provided the first estimates of diagnosis and treatment patterns, HCRU, and costsassociated with these conditions. These resource use and cost estimates highlight the need to developprevention strategies for HPV-related pathologies.

Costs and Resource Use Among Patients with Cervical Cancer, Cervical Intraepithelial Neoplasia, and Genital Warts in Algeria