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In recent decades, due to various circumstances, in Ukraine and around the world, insufficient attention is paid to preserving the ecological well-being of the environment. Man-caused load on the environment, including contamination of agricultural land with various xenobiotics, in particular heavy metals, in some regions exceeds acceptable levels. Their toxicity is realized slowly and is manifested by immunodeficiency of animals, and can also cause mutagenic, teratogenic and embryotoxic effects. This is observed not only as a result of the Chernobyl tragedy, but also the growing, unregulated use of mineral fertilizers, plant protection products, virtually no disposal of waste of various origins, as well as emissions from industrial, chemical and mining enterprises, vehicles, which poses a growing threat to health. animals and humans. Numerous researchers (in particular Kravtsiv, 2005, Fedoruk &amp; Humenyuk, 1999, Pylypiv &amp; Fedoruk, 2000, Rivis et al., 1995, Velychko, 2007) point out that a significant part of this belongs to the anthropogenic entry of heavy metals into the biosphere.&#x0D;Given the wide range of biological and toxic effects of xenobiotics in general, and heavy metals in particular, it should be noted that they cause not only problems in animal welfare, but also negatively affect the quality of products made from animals kept and raised in man-made contaminated areas. And hence the health of people, maintaining their ability to work, which is a national priority.&#x0D;It should be borne in mind that the ability to accumulate chemical, toxic elements by organisms is determined not only by the geochemistry of the environment, but also by the biological nature and biochemical chain through which organisms and the environment (soil-plant-animal- human). Therefore, it is especially important for animal husbandry to improve the feeding rations of animals kept under man-made load with the use of safe sorbents and biologically active additives, which will contribute to obtaining quality raw materials and quality food, including dairy and meat. This confirms that a particularly important task of science, including biological and veterinary in the field of environmental physiology is a comprehensive study of the harmful effects of anthropogenic and man-made factors on environmental objects, especially farm animals, which provide raw materials to the processing industry and human food. Particular attention needs to be paid to the development of effective measures to reduce the negative man-made pressure on bio-cenosis, including on productive animals kept in conditions of ecological, technogenic risk, optimization of physiological and technological parameters of their existence with application in feeding, effective, payback, correcting feed additives and biologically active substances that, undoubtedly, will promote improvement of quality and safety of production, which is used in human nutrition.

naukovo-tehnìčnij bûletenʹ deržavnogo naukovo-doslìdnogo kontrolʹnogo ìnstitutu veterinarnih preparatìv ta kormovih dobavok ì ìnstitutu bìologìï tvarin

PHYSIOLOGICAL-BIOCHEMICAL AND VETERINARY AND SANITARY EVALUATION OF MILK AND BEEF UNDER THE CONDITIONS OF TECHNOGENIC LOADING AND FEEDING OF FEED ADDITIVES