English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Blood glucose and glycosylated haemoglobin are the two vital biochemical tests widely prescribed for the therapeutic management of diabetes and require different anticoagulants during specimen collection. If both tests can be performed using single vacutainer, it reduces the laboratory costs at a larger scale and facilitates timely intervention. The anticoagulants NaF/Na2 EDTA and K2 EDTA are used conventionally for blood glucose and HbA1c estimations respectively for specimen collection. In the current study we have investigated whether NAF/Na2 EDTA can be used for HbA1c assay without the need of separate vacutainer i.e.K2EDTA. A total of 125 subjects (25 non-diabetic and 100 diabetic) were enrolled for this study. Parallel samples were collected in NaF/Na2 EDTA and K2 EDTA to compare HbA1c levels in both the anticoagulants. The stability of HbA1c was elucidated in both anticoagulants till 72hrs of collection. The HbA1c levels in both anticoagulants showed excellent correlation (R 2 : 0.998). Bland and Altman analysis revealed that the bias between methods is -0.22 to +0.22%. The changes in HbA1c levels were unaltered till 72 hrs of collection in NaF/Na2EDTA and K2EDTA (mean SD: 0.066 vs. 0.058; %CV: 0.94 vs. 0.81). These results conclude that the same vacutainer used for glucose estimation can be used even for HbA1c till 72 hr of collection thus preventing the need of second sampling specifically in monitoring diabetic control. This study emphasized that a single vacutainer of NaF/Na2EDTA can be used safely for both glucose and HbA1c assays.

Evaluation and Validation of Utility of BD Glucose Vacutainer for Glycosylated Hemoglobin Assay for Timely Therapeutic Management of Diabetes Mellitus