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Case Report Gastrointestinal stromal tumor (GIST) is a rare cancer of the digestive reported about 0.1%–3.0% of all gastrointestinal neoplasms, 10% of small-bowel tumors, and 10%–15% of all sarcomas. Gastrointestinal Stromal Tumour (GIST) and it’s coexistence with adenocarcinoma of colon is one of the rare event to occur and reported in Malaysia. Hereby, we reported a case of 70 years old lady presented with history of passing malaena. Esophagogastroduodenoscopy (OGDS) revealed mass at greater curvature of stomach. Biopsy reported as GIST. Subsequent Computed Tomography (CT) abdomen revealed incidental finding of circumferential bowel thickening at sigmoid colon, colonoscopy revealed circumferential mass at sigmoid colon, in which biopsy reported adenocarcinoma. Patient underwent sleeve gastrectomy and anterior resection however she developed complications from anastomotic leak and succumbed to her illness.

Dual Pathology: Synchronous Existence of Gastrointestinal Stromal Tumour (GIST) of Stomach and Adenocarcinoma of Colon