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Original Research Article Introduction: Iron deficiency anemia is a common problem presented in antenatal patients throughout the developing countries across the world. Its prevalence is estimated to be from 20–80% worldwide with a greater percentage in the third world countries. The higher prevalence of anemia in pregnancy is a cause of concern as it causes considerable morbidity and mortality. The problem of Iron deficiency is more severe in the poor rural and tribal pregnant female population of our country. Aims: We in the present study tried to evaluate the results of treatment of iron deficiency anemia in pregnant females with oral and parenteral iron supplements and evaluate the effects of the treatment on the hemoglobin and iron status. Methods: This prospective cross-sectional study was conducted in the Department of Obstetrics and Gynecology, Rajshahi Medical College Hospital, Rajshahi, Bangladesh for a period of 6 months (January to Jun-2019). The patients were randomly selected from those visiting the OPD of the Department of Obstetrics and Gynecology for ANC. A total of n=78 patients with anemia were included in the study. The patients were evaluated completely including a complete history, clinical examinations and laboratory investigations were ordered with a complete hematological profile including serum iron, serum folate levels, urine, and stool examination. After obtaining the results the patients were separated into three groups Group I, II, & III (mild, moderate and severe) anemia. The mild and moderate groups were given only oral iron supplementation for 2 months and severe anemia was treated with IV iron sucrose for 1 to 2 weeks followed by oral supplementation. Results: The mean age was 24.5 years. The mean Hb levels in Group I was 8.2 ± 2.6 gm/dl and in group II the mean Hb levels were 7.5 ± 1.9 gm/dl and in group III the levels were 6.5 ± 1.1 gm/dl. In the group I the mean Hb levels increased at 8 weeks to 10.4gm/dl. The serum iron pretreatment was 80μgm/dl and increased up to 90.5 μgm/dl at 4 weeks and 100.2 @ 8 weeks interval. In group II at 8 weeks the mean Hb levels were increased to 9.9gm/dl. The serum iron pretreatment was 77μgm/dl and increased up to 98.5 μgm/dl at 4 weeks and 105.5 @ 8 weeks interval. In the group III the mean Hb levels were increased to 8.1 gm/dl at the end of 4 weeks and 10.1 gm/dl at the end of 8 weeks. The serum iron levels pretreatment values were 62μgm/dl and increased to 99.0μgm/dl at the end of 4 weeks and 106.4μgm/dl at the end of 8 weeks. Conclusion: it can be concluded that Iron deficiency anemia is common in this group of pregnant females and the response of parenterally administered iron was better as compared to the oral administration of iron supplements and therefore parenteral administration of iron should be done whenever it is indicated without hesitation.

“A Comparative Study of Management of Anemia in Pregnancy by Oral and Parenteral Therapy”