English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Tools annual

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Presents the access of premium content as premium feature

Premium Content

Global: Zendy Plus annual

Global: Zendy Free Plan

Original Research Article IntroductionLarynx is one of the most common sites of head and neck carcinoma. Nasopharyngeal carcinoma is relatively uncommon. Juvenile nasopharyngeal angiofibroma is a very rare disease but gradually increase in the incidence in the current decade as compared to the 1980s suggesting that some evolving host-agentenvironmental interaction or probably a novel etiologic agent operating in this part of the world. Materials and method: Total 53 patients from ENT department, having laryngeal or nasopharyngeal masses are included in this prospective study. During operation, part of the tissue is taken in phosphate buffer solution for detection of EBV-LMP-1 by PCR and part of tissue is taken in formalin for histopathology. Result: Out of 35 cases of laryngeal masses, 32 patients (91.4%) are male, 14 patients (40%) are in 6 th decade, 22 patients (62.86%) are smoker, 20 patients (57.14%) presented with hoarsness of voice, 8 patients (22.86%) have mass in both vocal cord, 21 patients (60%) have moderately differentiated squamous cell carcinoma, 6 (17.14%) have vocal cord nodule, 2 (5.71%) have fibro-epithelial polyp with dysplasia, 2 (5.71%) have dysplasia, 2 (5,71%) have squamous cell papilloma with koilocytic changes. Remaining 2 patients have cavernous haemangioma and inverted papilloma. Out of 18 cases of nasopharyngeal masses, 14 patients (77.78%) are male, 5 patients (27.78%) are in 2 nd decade and 4 patients (22.22%) are in 6 th decade, 9 patients (50%) are smoker, 10 patients (55.56%) presented with swelling in cervical region, fever and weight loss, 9 patients (50%) have undifferentiated non-keratinizing nasopharyngeal carcinoma, 6 patients (33.33%) have nasopharyngeal angiofibroma. Remaining 3 patients have keratinizing squamous cell carcinoma and non-Hodgkin lymphoma. But EBVLMP-1 is not found in any laryngeal or nasopharyngeal cases in this study. Conclusion: Most of the laryngeal masses are diagnosed as moderately differentiated squamous cell carcinoma and most of the nasopharyngeal masses are non-keratinizing nasopharyngeal carcinoma followed by nasopharyngeal angiofibroma. EBV infection may not always be a leading cause of laryngeal or nasopharyngeal mass.

scholars journal of applied medical sciences

Correlation of Histopathological Types of Laryngeal and Nasopharyngeal Mass with PCR Detected Epstein - Barr virus (LMP-1) – A Hospital Based Prospective Study