English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Original Research Article Introduction: Chronic Obstructive Pulmonary Disease (COPD) is a chronic inflammatory disabling disease. It is a spectrum of airway disease characterized by the chronic bronchitis (airway obstruction) & emphysema (parenchymal destruction).The major cause for morbidity & mortality in worldwide is COPD &it is the fourth leading cause of death in world. Objective of the Study: To identify the most common bacterial organism isolated from sputum of COPD patients from Out Patient in National Institute of Diseases of the Chest & Hospital (NIDCH). Material & Methods: Patients who were >40 years old attended Medical OPD at National Institute of Diseases of the Chest & Hospital (NIDCH), Mohakhali, Dhaka, Bangladesh from January 2018 to December 2018, diagnosed with COPD and having symptoms of acute exacerbation were screened for participation. Samples were collected in sterile vial & sent within 2 hours to the central laboratory. Sputum sample to be deemed acceptable for analysis; Microbiological study done by using a low magnification lens (x100) reveals <10 epithelial cells & >25 leucocytes per field. Selected sputa were processed microbiologically for quantitative study following accepted laboratory method. Results: Total of 70 patients, fulfilling the inclusion & exclusion criteria, 40 male & 30 female with 57% & 43%. Out of 70 patients, 19 showed the overgrowth of the normal commensal in sputum, so only 51 patients (72%) showed growth with culture positive. In terms of age, the study group belongs to a wide range from 40 years to > 80 years with maximum patients (35%) belonging to the age group of 50 -60 years followed by 60-70 years (25%) and 40-50 years (21.88%), Streptococcus pneumonia (14 cases, 27%), Hemophilus influenza(10 cases, 20%), Pseudomonas aeruginosa (7 cases, 14%), Moraxella catarrhalis (6 cases, 12%), Eschericia coli (4 cases, 8%), Staphlococcus aureus (3 cases, 6%), Citrobacter freundii (3 cases, 6%), Klebsiella pneumonia (2 cases, 4%), Acinetobacter baumannii (1 case, 2%), Proteus mirabilis (1 case, 2%). The usual organisms which used to be considered responsible for AECOPD like S. Pneumonia, H. influenza were sensitive to commonly used antibiotics like cephalosporins aminoglycosides, fluoroquinolones. Conclusion: AE-COPD had serious negative impact on patient pulmonary function, quality of life as well as socioeconomic status. COPD can be triggered or exaggerated commonly by bacterial and viral infections with variable profile depending on the geographical areas. COPD has many aetiology, smoking and environmental pollution plays the major role in it.

Common Bacterial Isolates in Sputum of AE-COPD Patients in National Institute of Diseases of the Chest and Hospital (NIDCH)