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Original Research Article Objective: In this study our main goal is to evaluate the Antibiotic sensitivity pattern of Bacterial Isolates in Neonatal Septicemia in Bangladesh. Methods: This cross sectional study is conducted at Neonatal unit of the department of paediatrics, Sir Salimullah Medical College and Mitford Hospital, Dhaka, From July 2007 to June 2008.Among 90 clinically diagnosed septicemic neonates, 30 were blood culture positive. Results: During the study, 30 samples showed growth of different organisms, 12(40%) samples showed growth of klebsiella, 6 samples (20%) growth of coagulase negative staphylococcus, 5 samples (17%) were pseudomonas positive. 4 samples (13%) showed growth of E. coli. Here 18(60%) neonates developed late onset and 12(40%) early onset infection with various organisms. Ciprofloxacin was the most sensitive antibiotics against all organisms ranging from (4.0-100%) then was the chloramphenicol 20-83%. Ceftriaxone was (40-80%) sensitive against almost all organisms but E. coli were resistant to ceftriaxone. Gentamicin and Cotrimoxazole were sensitive to organisms from 0-66% and 0-40% respectively. Conclusion: From our result, we can conclude that, gram negative organisms remain as the main pathogens causing neonatal septicaemia with predominance of klebsiella. The emergence of kelbsiella species is a new one in this institution. Further study should be carried out to find out the source of this organism.

Antibiotic Sensitivity Pattern of Bacterial Isolates in Neonatal Septicemia in Bangladesh