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Original Research Article Objective: Hypothyroidism is the most common pathological hormone deficiency. This clinical state is due to either the decreased secretion or decreased action of thyroid hormones. These hormones have a profound effect on multiple organ systems, with the heart being particularly sensitive to this effect. Hence it is important to identify any clinical or sub clinical hypothyroidism at the earliest to blunt its cardiovascular effects. Aim: To assess the cardiovascular changes in newly diagnosed hypothyroid patients. Methods: Among the patients attending the Medicine OPD at Venkataeswara Hospital, Chennai-35. Newly detected hypothyroid patients were diagnosed based on their symptoms, clinical examination and hormone assays. These study subjects were subjected to detailed cardiovascular examination, ECG and echocardiography. Results: Out of 44 patients, who participated in the study, 27.3% patients had bradycardia; 22.7% had low voltage complexes; 20.5% had pericardial effusion; 11.3% had diastolic dysfunction. Systolic function was normal for all study subjects. Conclusion: This study provides a clinical profile on the cardiovascular effects of newly diagnosed hypothyroid patients. Early diagnosis and treatment of hypothyroidism with thyroxine helps to reduce these cardiovascular risks.

A Hospital-Based Cross-Sectional Study on Cardiovascular Changes in Newly Diagnosed Hypothyroid Patients