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Evidence has shown that C-reactive protein (CRP) levels are able to predict the risk of a variety of cardiovascular outcomes such as acute myocardial infarction (AMI), sudden cardiac arrest and peripheral arterial disease.1 The global probability of dying from myocardial infarction, stroke, cancer, chronic respiratory attacks and diabetes in 2016 was 18%, with a slightly higher risk for males (22%) than for females (15%).2 In South Africa, studies show the increased prevalence of cardiovascular disease risk factors in aged populations including hypertension, lipidaemia and cardiometabolic biomarkers.3-5 Many people are not aware of these risk factors increasing their probability of cardiovascular events and death.6 A previous study has shown that there is a close link between elevated serum CRP levels and increased vulnerability for disease and mortality in older patients.7 CRP has been found to be comparable to other confirmed cardiovascular risk factors namely, diabetes and hypertension.8

Evidence for the use of the Alere Afinion™ AS100 for measuring the levels of C-reactive protein in an elderly South African population