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Funding information Abstract: Introduction: Anthocleista vogelii soaked in ethanol among other solvent has been used traditionally for the acclaimed fertility enhancing properties especially in females Aims: This research was to investigate the claims from the traditional uses of Anthocliesta vogelii in enhancing fertility so as to provide scientific parameters to justify such assertions. Materials and Methods: The phytochemistry of the ethanolic leave extract of Anthocleista vogelii was determined prior to it being administered orally for 14 days to Wister albino rats. Micronor (norethisterone) or Nacetylcysteine (NAC) was given orally to induce temporary infertility in the female rats for seven (7) days prior to other treatment. The Blood samples from experimental animal groups were collected through cardiac puncture when the rats were sacrificed after the completion of fourteen (14) days extract administration. The hematological parameters were performed using the Sysmex® Automated Hematology Analyzer KX-21N. Biochemical evaluation of glutamic pyruvate transaminase ALT, alkaline phosphatase ALP, glutamic oxaloacetate transaminase AST, total cholesterol and total tryacylglycerol were done using Randox® biochemical kits. Results: The extract was found to possess Anthraquinones, Terpenoids, Flavonoids, Saponins, Alkaloids, Phenols and Phytosterols. The hematological parameters showed a significant increase (P<0.05) in absolute middle cells (basophils, eosinophils and monocytes) count. It also showed a significant reduction in the ALP, ASP, AST, TAG and cholesterol level (p<0.05). Conclusion: The results suggest that Anthocleista vogelii may play a role in creating the environment required for enhancing pregnancy and support the claims on the traditional use of Anthocliesta vogelii to enhance fertility in female.

BIOCHEMICAL AND HAEMATOLOGICAL BIOMARKER DETERMINED IN FEMALE ALBINO RATS INDUCED WITH INFERTILITY AND ADMINISTERED WITH ANTHOCLIESTA VOGELII