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HandiHaler ®.The article presents results of long-term (9 months) treatment of patients with chronic obstructive pulmonary disease (COPD) of II and III stages with inclusion of Spiriva ®HandiHaler ®in treatment programs. It is shown that under conditions of good compliance of patients’ comprehensive long-term treatment leads to improvement of clinical symptoms and lung ventilation function, increases oxygen saturation of arterial blood, and tissues, and in most cases stabilizes concentration of nitric oxide in exhaled air, although at a higher level than in healthy persons. All mentioned above improves physical activity of patients with COPD and characterizes high efficiency of long-term rehabilitation in application of Spiriva ®HandiHaler ®.

СТАН ПРОТЕЇНАЗ-ІНГІБІТОРНОЇ СИСТЕМИ У КУРЦІВ ХВОРИХ НА ХРОНІЧНЕ ОБСТРУКТИВНЕ ЗАХВОРЮВАННЯ ЛЕГЕНЬ