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Neonatal sepsis is defined as a clinical syndrome with systemic manifestations and bacteremia that occurs in the first month of life. Admnistration of antibiotics had to follow the pattern of the most common causal germs in a hospital. This study was aimed to determine the antibiotics of neonatal sepsis patients at the Neonatal Intensive Care Unit (NICU) of Prof. Dr. R. D. Kandou Hospital Manado, in this case types of antibiotics, duration of the used antibiotics, as well as the use of the first, second, and third-line antibiotics. This was a descriptive analytical study with a cross sectional design. Samples were neonatal sepsis patients who were treated with first, second, and third line antibiotic therapy at the NICU from September to November 2019. The results obtained a total of 40 patients, consisting of 22 males (55%) and 18 females (45%). The condition of the patients when coming out of the ward were 12 recovered (30%) and 28 died (70%). Combination antibiotics were the most common used as many as 37 cases (58%). The length of time using antibiotics based on lines, obtained that the first-line antibiotics were given at a duration of ≤5 days, while the second and third line antibiotics were more often given at a duration of >5 days. In conclusion, most neonatal sepsis patients were given antibiotics in combination. There were differences among the durations of the first, second and third line antibiotics used in patients with neonatal sepsis.

Analisis Penggunaan Antibiotik pada Pasien Sepsis Neonatorum di Neonatal Intensive Care Unit RSUP Prof. Dr. R. D. Kandou Manado