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: Endophytic fungi is a species of fungi which life on plant tissue system. Endophytic fungi can be isolated from the roots, stems and leave of the plant. Endophytic fungi can produce a substance potencial to be antibacteria. This research aimed to test the presence of antibacterial effect on an isolated leaf of mangrove plant Sonneratia alba towards Staphylococcus aureus and Escherichia coli. The method that is used for the antibacterial activity test, done by putting mycelia of endophytic fungi in combination media that has been smeared with Staphylococcus aureus and Escherichia coli. Obtained from research that has been made, it conducted two species of endophytic fungi that isolated from mangrove plant leaf Sonneratia alba. Both endophytic fungi has effect as antibacteria against Staphylococcus aureus and Escherichia coli, but the second type of endophytic fungi has more effective and stronger antibacterial effect compare to endophytic fungi type I and positive control. Keywords : antibacterial, endophytic fungi, mangrove Sonneratia alba Abstrak : Jamur endofit adalah jamur yang terdapat dalam sistem jaringan tumbuhan. Jamur endofit dapat diisolasi dari akar, batang dan daun tumbuhan. Jamur endofit dapat menghasilkan senyawa yang berpotensi sebagai antibakteri. Penelitian ini bertujuan untuk mengetahui ada tidaknya efek antibakteri jamur endofit daun Sonneratia alba terhadap bakteri Staphylococcus aureus dan Escherichia coli. Metode yang digunakan untuk uji antibakteri dilakukan dengan cara menempelkan miselia jamur endofit pada media agar kombinasi yang telah dioleskan bakteri uji. Dari penelitian yang dilakukan diperoleh dua jenis jamur endofit yang diisolasi dari daun tumbuhan mangrove Sonneratia alba. Kedua jamur endofit memiliki efek sebagai antibakteri terhadap kedua bakteri uji akan tetapi jamur endofit tipe II memiliki efek antibakteri yang lebih baik dibandingkan dengan jamur endofit tipe I dan kontrol positif. Kata kunci : antibakteri, jamur endofit, daun Sonneratia alba

UJI EFEK ANTIBAKTERI JAMUR ENDIFIT PADA DAUN MANGROVE Sonneratia alba TERHADAP BAKTERI UJI Staphylococcus aureus DAN Escherichia coli