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The population undergoing dialysis is aging and increasing around the world. A particularly problematic issue plaguing the elderly population is the frailty. Frailty is usually defined as “a state of increased vulnerability to stressors resulting from a decrease in physiologic reserves in multiple organ systems causing limited capacity to maintain homeostasis” [1]. There are two major approaches to assess frailty: one is frailty phenotype model developed by Fried et al. and the other is accumulated deficit model by Rockwood et al. While the most widely used assessment of frailty is Fried’s phenotype model, regardless of assessment method, frailty remains highly associated with an increased risk of several deleterious outcomes including disability, falls, hospitalization, institutionalization, and death [2].

Frailty Raises as a New Target in Patients with Chronic Hemodialysis in Any Country and the Problem We Should Solve