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Background: Vaginal metastasis, despite being rare, are more common than primary tumors and as presentation of the disease is extremely rare. At the time of diagnosis metastasis by hematogenous or lymphatic spread in 20-30% of patients. Case presentation: 68 years old female patient that debuted with haematuria. In the extension study we can objectify a left renal mass treated by laparoscopic radical nephrectomy. During admission the patient presented and episode of metrorragia. A lesion was found in the lower thrid of the vagina, which was biopsed, resulting a vaginal metastasis of clear cell carcinoma. The patient presented a favorable evolution being discharged four days after de surgical intervention. The subsequent extension study revealed progression of the underlying disease with mediastinal nodes and bone metastases.

Synchronous Vaginal Metastasis in Patient with Clear-Cell RCC. A Case Report and Review of the Literature