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Background: Blood is precious and there is no alternative for human blood. Proper utilization as well as rationale use of blood is necessary with minimal discarding of blood units and implementing various interventions that can be used to optimize blood and its components use by training and education. Aim: An analytical study of discarded units of whole blood and its components in a blood bank at a Tertiary care hospital in vadodara. Study designs and methods: Data on the number of discarded whole blood units and its components, reasons for discard, number of blood components processed as well as the number of collected blood units were obtained from blood bank records and registers. The data obtained was analyzed. Results: The total number of blood units collected from Jan 2016 to Dec 2018 was 13249 from which 36447 units of components were prepared. The total number of discarded whole blood units and its components was 5097. GJMR-C Classification: NLMC Code: WF 330 AnAnalyticalStudyofDiscardedUnitsofWholeBloodanditsComponentsinaBloodBankataTertiaryCareHospitalinVadodara Strictly as per the compliance and regulations of: Global Journal of Medical Research: C Microbiology and Pathology Volume 20 Issue 2 Version 1.0 Year 2020 Type: Double Blind Peer Reviewed International Research Journal Publisher: Global Journals Online ISSN: 2249-4618 & Print ISSN: 0975-5888 An Analytical Study of Discarded Units of Whole Blood and its Components in a Blood Bank at a Tertiary Care Hospital in Vadodara Ashu Dogra α & Devanshi Gosai σ AbstractBackground: Blood is precious and there is no alternative for human blood. Proper utilization as well as rationale use of blood is necessary with minimal discarding of blood units and implementing various interventions that can be used to optimize blood and its components use by training and education. Background: Blood is precious and there is no alternative for human blood. Proper utilization as well as rationale use of blood is necessary with minimal discarding of blood units and implementing various interventions that can be used to optimize blood and its components use by training and education. Aim: An analytical study of discarded units of whole blood and its components in a blood bank at a Tertiary care hospital in vadodara. Study designs and methods: Data on the number of discarded whole blood units and its components, reasons for discard, number of blood components processed as well as the number of collected blood units were obtained from blood bank records and registers. The data obtained was analyzed. Results: The total number of blood units collected from Jan 2016 to Dec 2018 was 13249 from which 36447 units of components were prepared. The total number of discarded whole blood units and its components was 5097. Platelets recorded the highest discard rate of 35.11% (3629/5097 units). Non utilization was the major cause of discard at 69.06% (3520/5097 units). Other causes of discard included TTI positivity 13.06% (666/5097 units), leakage 11.69% (596/5097 units), lipemic 2.29% (117/5097 units), underweight 0.58% (30/5097 units), clotted 0.54% (28/5097 units) and haemolysis 0.51% (26/5097 units). Conclusion: Properly implemented blood transfusion policies, training of staff notification of permanently deferred donors will help in discarding less number of blood bags from collected units. These discarded bags, because they are unutilized are both financially as well as socially harmful to blood bank.