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Background: Resistance training is the most effective way to increase muscle mass. The hormonal axis of GHIGF-1 is considered important for the health of the musculoskeletal system in both childhood and adulthood .The purpose of this study was to compare two types to resistance training with and without blood flow restriction on GHIGF-1 axis after the exercise. Methods: In this study, 36 adolescent gymnast boys aged 10 to 14 years participated in a quasi-experimental research design. The subjects (mean weight 37.11 ± 8.11 kg, height 145.16 ± 11.58 cm, body mass index 17.40 ± 1.77 kg m) were randomly divided into three groups; control (n=12), high intensity resistance training (n=12), and low intensity resistance training with blood flow restriction (n=12). Training protocol contained three motions included leg extension, elbow flexion and bench press. Blood samples were taken before and half an hour after

majallah-i pizishkī.

Comparison of growth hormone and insulin-like growth factor-1 responses to high intensity and low intensity resistance training with and without blood flow restriction in adolescent male athletes