English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Background: Composites used in the direct bonding of brackets in fixed orthodontics are considered a suitable environment for the multiplication of cariogenic bacteria and the establishment of microbial plaques by creating a distance between the bracket, tooth surface, and surface properties such as porosity. In the present study, we decided to combine curcumin-reduced nano-graphene oxide (rGO-NCUR) with a composite resin used in orthodontics to achieve a composite with optimal shear bond strength (SBS) and antimicrobial properties against Streptococcus mutans as a main cariogenic bacterium. Methods: In the present study, nanoparticle of graphene oxide (NGO) was synthesized by the modified Hummers’ method using graphite powder and reacted by NCUR to regenerate reduced-NGO (rGO-NCUR). Scanning electron microscopy (SEM) was used to confirm the synthesis of NGO, NCUR, and rGO-NCUR. SBS and antimicrobial activity of Transbond XT composite containing 5% rGO-NCUR were performed against S. mutans biofilms. SPSS software, one-way ANOVA test, and Tukey post hoc test with a significance level equal to or less than 0.05 were used to analyze the data. Results: The synthesis of NGO, NCUR, and rGO-NCUR in nanoscale was confirmed by SEM. The amount of SBS in the composite sample with 5% w/w rGO-NCUR was 12.30 ± 0.65 MPa. The optical density of S. mutans in the biofilm structure formed on composite containing 5% w/w rGO-NCUR was significantly reduced (62.10%) compared with the control group, namely, original composites used in orthodontics (P&lt;0.05). Conclusions: Based on the data of the present study, it can be concluded that composite containing 5% w/w rGO-CUR, without adverse effect on the physical-mechanical properties of composites, can be used as an antimicrobial additive of composites used in orthodontics to control biofilm formation and caries around orthodontic brackets.

Antimicrobial Properties and Shear Bond Strength of Composite Used in Orthodontics Following the Addition of Curcumin-Reduced Nanographene Oxide