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The study aimed at evaluating steroid biomarker genes ( ER α, PGR , ER β) and determining the expression level of estrogen-regulated genes ( SCUB2 and BCL2 ) and growth factors receptors (HER2 and IGFR1) in cancer tissue samples obtained from Iranian patients with breast cancer. Moreover, relationships with clinicopathologic aspects of tumor and response to treatment were studied.

Expression of SCUBE2 and BCL2 Predicts Favorable Response in ERα Positive Breast Cancer