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Aim: More than 400 million people worldwide are infected with the hepatitis B virus (HBV). The effect of HBV infection on pregnant women is unclear. The presence of chronic HBV in pregnancy has been reported to increase such maternal and fetal risks as gestational diabetes, antepartum hemorrhage, prematurity, neonatal jaundice, and low birth weight. The purpose of this study was to investigate the effects of HBV on pregnancy and fetal risks. Materials-Methods: Three hundred and one pregnant women infected with HBV and giving live birth in our hospital in 2014-2017, and their babies, were enrolled as the case group, while randomly selected pregnant women giving live birth in our hospital and not infected with HBV, and their babies, were included as the control group. Maternal and fetal outcomes such as type of delivery, miscarriage, re-eclampsia, gestational diabetes, antepartum hemorrhage, fetal distress, gestational weeks, and intrauterine growth restriction (IUGR) were analyzed retrospectively from patients’ records. Results: Delivery was by the normal vaginal route in 189 (62.8%) of the 301 HBsAg-positive women in the study, while diabetes was present in 4 (1.3%), pre-eclampsia in 2 (0.7%), a history of miscarriage in 82 (27.2%), and placental detachment in 5 (1.7%). No statistically significant difference was determined between these and the HBsAg-negative women (p>0.05). IUGR was present in the babies of 6 (2%) of HBsAg(+) mothers, and fetal distress in 12 (40%). The presence of fetal distress was significantly higher in the babies of HBsAg(+) mothers (p:0.036). Conclusion: Although several studies have shown that HBV infection increases maternal and fetal risks, only the risk of fetal distress was significant in our study. The noteworthy finding of our study is that the presence of HBV did not affect the physician’s decision regarding type of delivery.

Maternal Kronik Hepatit B Virüs Enfeksiyonu Gebelik ve Fetal Riskleri Artırıyor Mu?