English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Obesity affects more than a third of Americans and its prevalence is increasing in Brazilians. In severe cases, bariatric surgery is considered the most successful and long-lasting treatment. During the preoperative evaluation, secondary causes of obesity should be investigated and, specifically in Brazil, Cushing’s Syndrome (CS) should be excluded in these patients, despite controversial recommendations for CS screening in current guidelines. The prevalence of endogenous SC is extremely low, but appears to be higher in specific populations, such as diabetics, patients with resistant hypertension or those with obesity. Aim: To evaluate the prevalence of positive screening for CS in obese candidates for bariatric surgery and to discuss possible risk factors or comorbidities associated with screening positivity. Material and Methods: A retrospective study was conducted with 629 patients attended at the Obesity Outpatient Clinic of Santa Casa, Belo Horizonte between 2008 and 2016. CS screening was performed with a 1mg dexamethasone (1mg-DST) suppression test, dosing cortisol in the next morning (cut-off point ≥1.8μg / dL). Results: 80 of the 629 patients had positive screening for SC. Of these, 20 patients were considered negative after repeated 1mg-DST and 6 patients were negative after the Liddle 1 test. Conclusion: The prevalence of positive screening for SC was 12.7%, similar to the literature. No risk factor or co-morbidity could be directly associated with the positivity of the screening test. Key-words: Cushing’s Syndrome; Obesity, Morbid; Bariatric Surgery. Submetido: 05/04/2019 Aceito: 23/12/2019 Marcella Menezes Andrade1 Beatriz Mota Tiburcio2 Vinícius Alves Lima3 Silvana Pinheiro Neiva1 Cláudia Maria Andrade Fernandes1 1Santa Casa de Misericórdia de Belo Horizonte, Brasil. 2Hospital Madre Tereza, Brasil. 3Hospital Metropolitano Odilon Behrens, Brasil. Prevalência de rastreio positivo para síndrome de Cushing em indivíduos obesos candidatos ao tratamento cirúrgico para obesidade Prevalence of positive screening for Cushing’s syndrome in obese individuals who are candidates for bariatric surgery