English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

Colorectal obstruction caused by colorectal cancer has been reported to occur in 7%–29% of all patients with colorectal cancers [1, 2], with left-sided colonic obstruction being more common than right-sided colonic obstruction [3]. Massive colonic distension, localized or generalized peritonitis, fluid and electrolyte imbalance, colonic wall necrosis, and perforation may develop as a result of colorectal obstruction. If a colorectal obstruction does occur, urgent decompression, surgical or medical, is needed. Obstruction or perforation of a colorectal carcinoma in an emergency situation may be associated with worse oncological outcomes and a higher incidence of local spread and metastatic disease [4]. Emergency operations are associated with mortality in 15%–34% of patients and morbidity in 32%–64% [2, 3]. Surgical management of an acute malignant left-sided colorectal obstruction remains controversial. In emergency situations, several operative strategies are available to the surgeon, including 2-stage surgery involving primary resection with a colostomy or proximal colostomy followed by resection and 1-stage surgery involving a primary resection with anastomosis. One-stage procedures seem to be superior to 2or 3-stage procedures in terms of morbidity and mortality. Although few studies regarding 1-stage procedures for the treatment of patients with malignant left-sided colorectal obstruction have been published, recent guidelines recommend either a segmental colectomy and primary anastomosis in cases involving rectal anastomosis or preexisting continence disturbance or a subtotal colectomy and primary anastomosis in cases involving cecal wall necrosis, colon perforation or serosal tear, or synchronous colonic tumor [5]. In 2or 3-stage procedures, restoration of the stoma requires a second major operation due to the patient’s old age, poor general condition and combined disease. Restoration of the stoma is performed in only 60% of cases, and its morbidity rate is about 40% [6]. Patients with a colostomy have poorer health-related quality of life than do patients without a colostomy. A self-expandable metallic stent (SEMS), as a bridge to surgery, might be a useful option for 1-stage surgery without a colostomy. Its clinical success rate is 84% to 94%, the stent migration rate is 12%, the reobstruction rate is 7%, and the clinical stent perforation rate is 4%–6.9% [7, 8]. The stent-procedure-related mortality in patients with colonic obstruction is reported to be less than 1% [8]. Placement of the SEMS can decompress the colon, enabling conversion of an emergency surgery to an elective one with successful primary anastomosis without a colostomy. The SEMS procedure allows the surgeon to perform elective laparoscopic surgery on patients with an acute malignant left-sided colorectal obstruction. Laparoscopic surgery for such patients has many advantages, including a reduced number of sequential operations, a reduction in stoma requirements, and a reduction in overall morbidity and mortality. Nevertheless, we have to admit that the SEMS has an adverse effect on the 5-year overall and disease-free survival rates [9]. In this study, 94 consecutive patients with left colon cancer obstruction who received an emergency subtotal colectomy or SEMS insertion as elective surgery were enrolled. A subtotal colectomy was attempted in 24 patients, and preoperative SEMS insertion was attempted in 70 patients. Laparoscopic surgery was performed more frequently on the patients in the SEMS group (62 of 70, 88.6%) compared with patients in the subtotal colectomy group (4 of 24, 16.7%). Total hospital stay was shorter in the subtotal colectomy group. The median number of bowel movements in the subtotal colectomy group was twice per day at postoperative 3–6 months. A subtotal colectomy for the treatment of paCorrespondence to: Byung Chun Kim, M.D. Department of Surgery, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, 1 Singil-ro, Yeongdeungpo-gu, Seoul 07441, Korea Tel: +82-2-829-5130, Fax: +82-2-849-4469, E-mail: bckimgs@hallym.or.kr

Comparison of a Subtotal Colectomy With Self-Expandable Metallic Stent in the Management of Patients With Obstructive Left Colon Cancer