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In this work, a surface plasmon resonance (SPR) biosensor based on two-dimensional transition metal dichalcogenides (TMDCs) is proposed to improve the biosensor&amp;rsquo;s sensitivity. In this sensor, different kinds of two-dimensional TMDCs are coated on both surfaces of metal film. By optimizing the structural parameters, the angular sensitivity can reach as high as 315.5 Deg/RIU with 7-layers WS₂ and 36 nm Al thin film, which is 3.3 times of the conventional structure based on single Al thin film. We also obtain maximum phase sensitivity (3.85 &amp;times; 10⁶ Deg/RIU) with bilayer WS₂ and 35 nm Al thin film. The phase sensitivity can be further improved by employing Ag and removing air layer. The proposed configuration is of great potential for biochemical sensing.

Sensitivity Enhancement in Surface Plasmon Resonance Biochemical Sensor Based on Transition Metal Dichalcogenides/Graphene Heterostructure