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In this paper, we present a simple and feasible electrochemical sensor based on Au nanoparticle-functionalized graphene for the determination of sulfanilamide. Au nanoparticles were deposited on graphene, which acted as a platform to prepare excellent nanocomposites. Attributed to the graphene's large surface area and the Au nanoparticles' strong conductivity, many sulfanilamide molecules were enriched on the sensor surface and the signal response became more sensitive. Under the optimal conditions, the electrochemical sensors could be used for the efficient detection of sulfanilamide. Good linearity was observed in the range of 0.1-1000 μmol·L -1 and the detection limit was 0.011 μmol·L -1 . Most importantly, the Au nanoparticle-functionalized graphene-modified electrode could be successfully applied for the detection of sulfanilamide in animal meat, and exhibited good stability, acceptable recovery, and offered a promising platform for point-of-care detecting in real samples.

Modifications of Au Nanoparticle-Functionalized Graphene for Sensitive Detection of Sulfanilamide