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3D X-ray Computed Tomography (CT) is used in medicine and non-destructive testing (NDT) for industry to visualize the interior of a volume and control its healthiness. Compared to analytical reconstruction methods, model-based iterative reconstruction (MBIR) methods obtain high-quality reconstructions while reducing the dose. Nevertheless, usual Maximum-A-Posteriori (MAP) estimation does not enable to quantify the uncertainties on the reconstruction, which can be useful for the control performed afterwards. Herein, we propose to estimate these uncertainties jointly with the reconstruction by computing Posterior Mean (PM) thanks to Variational Bayesian Approach (VBA). We present our reconstruction algorithm using a Gauss-Markov-Potts prior model on the volume to reconstruct. For PM calculation in VBA, the uncertainties on the reconstruction are given by the variances of the posterior distribution of the volume. To estimate these variances in our algorithm, we need to compute diagonal coefficients of the posterior covariance matrix. Since this matrix is not available in 3D X-ray CT, we propose an efficient solution to tackle this difficulty, based on the use of a matched pair of projector and backprojector. In our simulations using the Separable Footprint (SF) pair, we compare our PM estimation with MAP estimation. Perspectives for this work are applications to real data as improvement of our GPU implementation of SF pair.

Variational Bayesian Approach in Model-Based Iterative Reconstruction for 3D X-Ray Computed Tomography with Gauss-Markov-Potts Prior