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The local medicinal plant  Rhazya stricta Decne  is reviewed for its folkloric medicinal, phytochemical, pharmacological, biological, and toxicological features.  R. stricta  has been used widely in different cultures for various medical disorders. The phytochemical studies performed on the  R. stricta  extract revealed many alkaloidal and fatty acid compounds. Moreover, several flavonoid and terpenoid compounds were also detected. Pharmacological activates of  R. stricta  extracts are approved to possess antimicrobial, antioxidant, anticancer, antidiabetic, and antihypertensive activities. Additionally,  R. stricta  extract was found to hold biological activates such as larvicidal and phytoremediation activates  R. stricta  extract was found to be toxic, genotoxic, and mutagenic.  R. stricta  contains novel phytochemical compounds that have not been investigated pharmacologically. Further research is needed through in vitro and in vivo experiments to pave the road for these compounds for medical, veterinary, and ecological uses.

A Review of Rhazya stricta Decne Phytochemistry, Bioactivities, Pharmacological Activities, Toxicity, and Folkloric Medicinal Uses