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Chlamydia trachomatis ,  Mycoplasma genitalium , herpes simplex virus (HSV) and human papillomavirus (HPV) cause sexually transmitted infections. In addition, human herpesvirus 6 (HHV-6) may be a genital co-pathogen. The prevalence rates of HSV, HHV-6, HPV,  M. genitalium , and the  C. trachomatis ompA  genotypes were investigated by PCR in urogenital samples of the  C. trachomatis  nucleic acid amplification test positive (n = 157) and age-, community- and time-matched negative (n = 157) women. The prevalence of HPV DNA was significantly higher among the  C. trachomatis  positives than the  C. trachomatis  negatives (66% vs. 25%,  p  < 0.001). The prevalence of HSV (1.9% vs. 0%), HHV-6 (11% vs. 14%), and  M. genitalium  DNA (4.5% vs. 1.9%) was not significantly different between the  C. trachomatis -positive and -negative women. Thirteen per cent of test-of-cure specimens tested positive for  C. trachomatis . The prevalence of HSV, HHV-6, HPV,  M. genitalium , and the  C. trachomatis ompA  genotypes did not significantly differ between those who cleared the  C. trachomatis  infection (n = 105) and those who did not (n = 16). The higher prevalence of HPV DNA among the  C. trachomatis  positives suggests greater sexual activity and increased risk for sexually transmitted pathogens.

pathogens

The Prevalence of HSV, HHV-6, HPV and Mycoplasma genitalium in Chlamydia trachomatis positive and Chlamydia trachomatis Negative Urogenital Samples among Young Women in Finland