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The genus  Paris  is an excellent source of steroidal saponins that exhibit various bioactivities.  Paris mairei  is a unique species and has been widely used as folk medicine in Southwest China for a long time. With the help of chemical methods and modern spectra analysis, five new steroidal saponins, pamaiosides A–E ( 1 – 5 ), along with five known steroidal saponins  6 – 10 , were isolated from the rhizomes of  Paris mairei . The cytotoxicity of all the new saponins was evaluated against human pancreatic adenocarcinoma PANC-1 and BxPC3 cell lines.

New Steroidal Saponins Isolated from the Rhizomes of Paris mairei