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Using citric acid (CA) and ethylenediamine (EDA) as precursors, stable nitrogen-doped carbon dots (CD) nanosols were prepared by microwave procedure and characterized in detail. It was found that CD N s catalyze ethanol (Et)-HAuCl 4 to generate gold nanoparticles (AuNPs), which have strong surface plasmon resonance, Rayleigh scattering, (RRS) and a surface plasmon resonance (SPR) absorption (Abs) effect at 370 nm and 575 nm, respectively. Compled the new catalytic amplification indicator reaction with the specific As 3+ aptamer reaction, a new RRS/Abs dual-mode aptamer sensor for the assay of trace As 3+ was developed, based on the RRS/Abs signals increasing linearly with As 3+ increasing in the ranges of 5-250 nmol/L and 50-250 nmol/L, whose detection limits were 0.8 nmol/L and 3.4 nmol/L As 3+ , respectively. This analytical method has the advantages of high selectivity, simplicity, and rapidity, and it has been successfully applied to the detection of practical samples.

A Simple and Sensitive Nanogold RRS/Abs Dimode Sensor for Trace As3+ Based on Aptamer Controlled Nitrogen Doped Carbon Dot Catalytic Amplification