English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Two new octanorlanostane-type triterpenes, euphraticanoids A and B ( 1  and  2 ), two new trinorsesquiterpenoids, euphraticanoids C and D ( 3  and  4 ), and eight known triterpenoids ( 5 ,  6 ,  8 – 13 ) along with one steroid ( 7 ) were isolated from  Populus euphratica  resins. The structures of these new compounds, including their absolute configurations, were characterized by spectrocsopic, chemical, and computational methods. Biological evaluation revealed that compounds  4 ,  7 – 9 ,  12 , and  13  display neuroprotective activities in H 2 O 2 -induced HT-22 cells with  4 ,  8 , and  9  occurring in a concentration-dependent manner and  7 ,  12 , and  13  reaching the maximum effects at 20 μM. Meanwhile, the neuroprotective properties of all isolates were accessed using glutamate-induced SH-SY5Y cells and disclosed that compounds  3 ,  4 ,  8 , and  9  could dose-dependently protect neural cell injury in a concentration range of 10–40 μM. Finally, a brief structure–activity relationship was briefly discussed.

Neuroprotective Norsesquiterpenoids and Triterpenoids from Populus euphratica Resins