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The amount of boron accumulated in tumor tissue plays an important role regarding the success of the boron neutron capture therapy (BNCT). In this article, we report a modular system, combining readily available starting materials, like glycine, 1,3,5-triazine and the well-known 9-mercapto-1,7-dicarba- closo -dodecaborane(12), as well as α-d-galactopyranose for increased hydrophilicity, with a novel boron-rich tris- meta -carboranyl thiol.

molecules/molecules online/molecules annual

Enlargement of a Modular System—Synthesis and Characterization of an s-Triazine-Based Carboxylic Acid Ester Bearing a Galactopyranosyl Moiety and an Enormous Boron Load