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Three previously undescribed biflavonoids, oxytrodiflavanone A ( 1 ), and oxytrochalcoflavanones A,B ( 2 , 3 ), were isolated from the aerial part of Oxytropis chiliophylla , together with their putative biosynthetic monomers, i.e., (2 S )-5,7-dihydroxyflavanone ( 4 ), (2 S )-7-hydroxyflavanone ( 5 ), and 2',4'-dihydroxychalcone ( 6 ). The structures of these compounds were elucidated by a combination analysis of spectroscopic data. The cytotoxic activities of all the isolated compounds against PC-3 human prostate cancer cell line are also presented.

Oxytrodiflavanone A and Oxytrochalcoflavanones A,B: New Biflavonoids from Oxytropis chiliophylla