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Anxiety disorders and schizophrenia are common public health issues. The dried stigma of the plant  Crocus sativus  L., ( C. sativus ) commonly known as saffron are used in folk medicine for various purposes. Several lines of evidence suggest that  C. sativus , crocins and safranal are implicated in anxiety and schizophrenia. Here, I intend to critically review advances in research of these emerging molecules for the treatment of anxiety and schizophrenia, discuss their advantages over currently used anxiolytics and neuroleptics, as well remaining challenges. Current analysis shows that  C. sativus  and its components might be a promising class of compounds for the treatment of the above mentioned psychiatric diseases.

Constituents of Saffron (Crocus sativus L.) as Potential Candidates for the Treatment of Anxiety Disorders and Schizophrenia