English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

In connection with synthetic applications, we have foreseen to study the reactivity of the poorly reactive tert-butyl acrylate electrophile with chiral imines of unsymmetrical ketones, using conventional or microwave flash heating under carefully controlled reaction conditions in order to develop a selective and efficient access to the corresponding Michael adducts in which a created stereogenic quaternary carbon center was fully stereocontrolled. Depending on the conditions, either a keto ester or a lactam were obtained. A good correlation was obtained between experiment and theoretical calculations. The stereoselectivity of the process (e>95%) was determined using natural abundance 13 C-{ 1 H} NMR in a chiral polypeptide liquid crystal. The scope of the reaction was screened using a set of electrophilic alkenes giving Michael adducts in good yield and similar high enantiocontrol. SciForum

&lt;strong&gt;Chiral imines on the wave: reactivity of &lt;em&gt;tert&lt;/em&gt;-butyl acrylate and stereoselectivity determination using NMR in liquid crystals&lt;/strong&gt;